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| League History Index | Players | Teams | Managers | Leagues | Leaderboards | Awards | Accomplishments |
| Rank | Player | HR | YEAR | Open Career Leaderboard |
|---|---|---|---|---|
| 1 | David Santos# | 22 | 2049 | |
| 2 | Alfonso Harlan# | 15 | 2049 | |
| 3 | Natale Cimino# | 13 | 2049 | |
| 3 | Aaron Kaplan# | 13 | 2049 | |
| 5 | Armando Majano# | 12 | 2049 | |
| 6 | Danny Salinas# | 11 | 2049 | |
| 6 | Jimmy Lung# | 11 | 2049 | |
| 6 | Francisco Ballagas# | 11 | 2049 | |
| 9 | Frank Esquivel# | 10 | 2049 | |
| 9 | Kolenka Afrosimov# | 10 | 2049 | |
| 11 | Joe DiSantis# | 8 | 2049 | |
| 11 | Ryan Reagan# | 8 | 2049 | |
| 11 | Josh Benavidez# | 8 | 2049 | |
| 11 | Rob Burke# | 8 | 2049 | |
| 15 | Nick Travis# | 5 | 2049 | |
| 16 | Nelson Sancho# | 4 | 2049 |
