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| Name | Pos | Team | Age | DOB | POB | Nationality | Bats | Throws | Height | Weight | Salary |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Sabato, Miguel | CF | Great Lakes Loons | 20 | 11/18/2027 | Acarigua | VEN | Right | Left | 6' 0" | 190 lbs | - |
| Salazar, Juan | CF | Houston Orange Kings | 22 | 11/22/2025 | Santiago | DOM | Right | Right | 6' 3" | 195 lbs | - |
| Sanchez, Hector | 1B | Monterrey Jacks | 20 | 12/20/2027 | La Vega | DOM | Right | Right | 6' 0" | 180 lbs | - |
| Sanchez, Ivan | C | Great Lakes Loons | 21 | 06/22/2027 | Santa Teresa | VEN | Right | Right | 6' 2" | 200 lbs | - |
| Sanchez, Juan | RP | Brownsville Brown Cows | 18 | 01/05/2030 | Acapulco | MEX | Right | Right | 6' 0" | 165 lbs | - |
| Sanchez, Tony | SP | Free Agent | 35 | 12/20/2012 | Havana | CUB | Left | Right | 6' 1" | 200 lbs | - |
| Santiago, Luis | SP | Free Agent | 20 | 11/06/2028 | Maracaibo | VEN | Left | Right | 6' 8" | 200 lbs | - |
| Saunders, Erik | CF | Arlington Trappers | 21 | 08/10/2027 | Walnut Creek | USA | Left | Left | 6' 2" | 200 lbs | - |
| Schafer, Karl | C | Tulsa Drillers | 22 | 12/20/2025 | Havre | USA | Switch | Right | 6' 0" | 190 lbs | - |
| Schaffner, Bob | RP | Arlington Trappers | 22 | 01/06/2026 | Wheeling | USA | Left | Right | 6' 5" | 205 lbs | - |
| Schneider, Jerry | C | Monterrey Jacks | 22 | 03/30/2026 | Simi Valley | USA | Right | Right | 6' 2" | 205 lbs | - |
| Sekiya, Naoki | 1B | Da Nang Dolphins | 19 | 01/07/2029 | Osaka | JPN | Right | Right | 6' 0" | 200 lbs | - |
| Senz, Luke | SP | Free Agent | 27 | 05/22/2021 | Union Beach | USA | Left | Right | 6' 4" | 205 lbs | - |
| Serna, Antonio | RP | Schenectady Grasshoppers | 23 | 08/12/2025 | Guacimo | CRC | Right | Right | 6' 2" | 185 lbs | - |
| Serna, Esteban | 1B | Moscow Mules | 21 | 03/28/2027 | San Felipe | VEN | Right | Right | 6' 2" | 195 lbs | - |
| Serrano, Alexis | SP | Killarney Lakes | 21 | 08/25/2027 | San Pedro de Macorís | DOM | Left | Right | 6' 5" | 200 lbs | - |
| Servergnini, Felice | SS | Baxter Dingos | 19 | 08/25/2029 | La Asunción | VEN | Right | Right | 6' 4" | 180 lbs | - |
| Seto, Sze | RF | Traverse City Cherries | 19 | 04/03/2029 | Sydney | AUS | Left | Left | 6' 1" | 185 lbs | - |
| Shea, Chris | RP | Flagstaff Skyhawks | 31 | 07/07/2017 | Spartanburg | USA | Right | Right | 6' 2" | 200 lbs | - |
| Sibley, Mike | LF | Houston Orange Kings | 23 | 07/22/2025 | Lakewood | USA | Left | Right | 6' 2" | 170 lbs | - |
| Silva, Jonathan | RP | Baxter Dingos | 19 | 06/12/2029 | Santo Domingo | DOM | Right | Right | 5' 11" | 170 lbs | - |
| Simko, Mark | RF | Baxter Dingos | 21 | 09/04/2027 | Kechi | USA | Switch | Right | 6' 1" | 185 lbs | - |
| Simmons, Rich | SP | Houston Orange Kings | 19 | 09/22/2029 | Parma | USA | Left | Right | 6' 0" | 175 lbs | - |
| Solano, Rodolfo | SP | Arlington Trappers | 19 | 02/15/2029 | Santo Domingo | DOM | Right | Right | 6' 2" | 180 lbs | - |
| Soto, Emilio | CL | Great Lakes Loons | 20 | 03/03/2028 | Araure | VEN | Right | Right | 6' 6" | 200 lbs | - |
| Spijker, Mitchell | C | Great Lakes Loons | 20 | 11/20/2027 | Santa Cruz | ARU | Right | Right | 5' 11" | 185 lbs | - |
| Spring, Steve | 2B | Baxter Dingos | 20 | 12/14/2027 | Virginia Beach | USA | Right | Right | 6' 6" | 190 lbs | - |
| Squillari, Jose | RP | Flagstaff Skyhawks | 22 | 03/20/2026 | Anaco | VEN | Right | Right | 6' 2" | 190 lbs | - |
| Stafford, Chad | C | Lincolnville Abes | 23 | 10/23/2025 | Chandler | USA | Right | Right | 6' 1" | 195 lbs | - |
| Stevens, Jeremy | RP | Monterrey Jacks | 21 | 06/20/2027 | Kendale Lakes | USA | Right | Left | 6' 6" | 205 lbs | - |
| Stobbie, Eddie | RP | Concord Blue Devils | 20 | 12/17/2027 | Walpeup | AUS | Right | Right | 5' 10" | 165 lbs | - |
| Stoltz, Danny | LF | Brownsville Brown Cows | 23 | 06/20/2025 | Norwalk | USA | Right | Right | 6' 5" | 205 lbs | - |
| Stone, Paul | SP | Baxter Dingos | 22 | 09/25/2026 | Ionia | USA | Right | Right | 6' 2" | 185 lbs | - |
| Suarez, Mike | CL | Monterrey Jacks | 22 | 11/05/2026 | Cary | USA | Left | Left | 6' 2" | 180 lbs | - |
| Suffel, Kenny | SP | Monterrey Jacks | 20 | 11/09/2028 | Granite Hills | USA | Right | Left | 6' 1" | 175 lbs | - |
| Sutton, Chris | 1B | Da Nang Dolphins | 20 | 11/27/2027 | Braintree | USA | Right | Right | 6' 0" | 185 lbs | - |
